The active substances in Calmurid HC are hydrocortisone acetate and urea. Hydrocortisone acetate is one of the adrenal hormones or corticosteroids. It inhibits inflammation, flaking, itch and swelling. Urea improves the absorption of water through the skin, making it softer. Flakes can disappear quickly. In addition, urea ensures that hydrocortisone acetate better able to penetrate into the skin. This combination is used in many skin conditions. It is mainly prescribed for eczema, seborrheic dermatitis, itching and psoriasis.