Panadol plus contains the active ingredients paracetamol and caffeine. Paracetamol (acetaminophen) relieves pain and lowers fever. Caffeine increases the analgesic effect of paracetamol and is uplifting. It can be used in different types of pain; headaches, migraines, fever, flu, colds, sore throat, sinusitis, middle ear infection, muscle pain, joint pain and menstrual symptoms.